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nervous, immune, bone, cartilage, blood, and of course the skin on our face that causes us to age

Multiple cellular processes are considered to contribute to this functional decline and these are collectively referred to as the hallmarks of aging and these include processes like genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, disabled macroautophagy, deregulated nutrient-sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, altered intercellular communication, chronic inflammation, and dysbiosis 1

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Estrogen and Sex Drive: What Changes in Midlife Shifting estrogen levels can spur a few changes that can, in turn, impact your sexual wellness: During perimenopause: Before estrogen completely disappears, its levels wildly fluctuate, which creates inconsistent symptoms and unpredictable desire